Online courses directory (19947)

We will explore the mathematical strategies behind popular games, toys, and puzzles. Topics covered will combine basic fundamentals of game theory, probability, group theory, and elementary programming concepts. Each week will consist of a lecture and discussion followed by game play to implement the concepts learned in class.

Since the discovery of the structure of the DNA double helix in 1953 by Watson and Crick, the information on detailed molecular structures of DNA and RNA, namely, the foundation of genetic material, has expanded rapidly. This discovery is the beginning of the "Big Bang" of molecular biology and biotechnology. In this seminar, students discuss, from a historical perspective and current developments, the importance of pursuing the detailed structural basis of genetic materials.

This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate.

This course explores the major areas of cellular and molecular neurobiology, including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell-type determination, axon guidance, neuronal cell biology, neurotrophin signaling and cell survival, synapse formation and neural plasticity. Material includes lectures and exams, and involves presentation and discussion of primary literature. It focuses on major concepts and recent advances in experimental neuroscience.

This course considers molecular control of neural specification, formation of neuronal connections, construction of neural systems, and the contributions of experience to shaping brain structure and function. Topics include: neural induction and pattern formation, cell lineage and fate determination, neuronal migration, axon guidance, synapse formation and stabilization, activity-dependent development and critical periods, development of behavior.

This course introduces the mathematical modeling techniques needed to address key questions in modern biology. An overview of modeling techniques in molecular biology and genetics, cell biology and developmental biology is covered. Key experiments that validate mathematical models are also discussed, as well as molecular, cellular, and developmental systems biology, bacterial chemotaxis, genetic oscillators, control theory and genetic networks, and gradient sensing systems. Additional specific topics include: constructing and modeling of genetic networks, lambda phage as a genetic switch, synthetic genetic switches, circadian rhythms, reaction diffusion equations, local activation and global inhibition models, center finding networks, general pattern formation models, modeling cell-cell communication, quorum sensing, and finally, models for Drosophila development.

This seminar explores experiments in education and discusses how education and learning might be done, through reading and discussion. This seminar is not a survey of experiments in education, but rather, its goal is to determine how learning should happen and what kinds of contexts allow it to happen.

MIT students are challenged daily to solve for x, to complete four problem sets, two papers, and prepare for an exam worth 30% of their grade... all in one night. When they do stop to breathe, it's for a shower or a meal. What does this have to do with creative writing? Everything. Creative writing and MIT go together better than you might imagine.

This seminar introduces, through studio projects, the basic principles regarding the use of color in the visual arts. Students explore a range of topics, including the historical uses of color in the arts, the interactions between colors, and the psychology of color.

This course considers a range of philosophical questions about the foundations of morality, such as whether and in what sense morality is objective, the nature of moral discourse, and how we can come to know right from wrong.

This course covers amino acid sequence control of protein folding, misfolding, amyloid polymerization and aggregation. Readings and discussions address topics such as chaperone structure and function, folding and assembly of fibrous proteins, and pathologies associated with protein misfolding and aggregation in Alzheimer's, Parkinson's, Huntington's and other protein deposition diseases. Students are required to write and present a research paper.

This is a seminar based on research literature. Papers covered are selected to illustrate important problems and approaches in the field of computational and systems biology, and provide students a framework from which to evaluate new developments.

The MIT Initiative in Computational and Systems Biology (CSBi) is a campus-wide research and education program that links biology, engineering, and computer science in a multidisciplinary approach to the systematic analysis and modeling of complex biological phenomena. This course is one of a series of core subjects offered through the CSB Ph.D. program, for students with an interest in interdisciplinary training and research in the area of computational and systems biology.

The course focuses on casting contemporary problems in systems biology and functional genomics in computational terms and providing appropriate tools and methods to solve them. Topics include genome structure and function, transcriptional regulation, and stem cell biology in particular; measurement technologies such as microarrays (expression, protein-DNA interactions, chromatin structure); statistical data analysis, predictive and causal inference, and experiment design. The emphasis is on coupling problem structures (biological questions) with appropriate computational approaches.

Lectures and discussions in this course cover the clinical, behavioral, and molecular aspects of the brain aging processes in humans. Topics include the loss of memory and other cognitive abilities in normal aging, as well as neurodegenerative conditions such as Parkinson's and Alzheimer's diseases. Discussions based on readings taken from primary literature explore the current research in this field.

Consists of a series of hands-on laboratories designed to give students experience with common techniques for conducting neuroscience research. Included are sessions on anatomical, ablation, neurophysiological, and computer modeling techniques, and ways these techniques are used to study brain function. Each session consists of a brief quiz on assigned readings that provide background to the lab, a lecture that expands on the readings, and that week's laboratory. Lab reports required. Students receive training in the art of scientific writing and oral presentation with feedback designed to improve writing and speaking skills. Assignments include two smaller lab reports, one major lab report with revision, and an oral report.

This course proposes that investigating the ways in which territory is produced, maintained and strategized, generates conflicts, establishes divisions, and builds identities can lead to a more critical understanding of architecture's role in society. This course is designed to expand the student's literacy in the concept of territory and its relation to the realm of architecture.

This course discusses the fundamental material science behind amorphous solids, or non-crystalline materials. It covers formation of amorphous solids; amorphous structures and their electrical and optical properties; and characterization methods and technical applications.

This course surveys the history of the Middle East, from the end of the 19^th century to the present. It examines major political, social, intellectual and cultural issues and practices. It also focuses on important events, movements, and ideas that prevailed during the last century and affect its current realities.

This graduate-level course introduces students to some fundamental 2D random objects, explains how they are related to each other, and explores some open problems in the field.

Surveys general principles and specific examples of motor control in biological systems. Emphasizes the neural mechanisms underlying different aspects of movement and movement planning. Covers sensory reception, reflex arcs, spinal cord organization, pattern generators, muscle function, locomotion, eye movement, and cognitive aspects of motor control. Functions of central motor structures including cerebellum, basal ganglia, and cerebral cortex considered. Cortical plasticity, motor learning and computational approaches to motor control, and motor disorders are discussed.