Online courses directory (2511)
This course studies representative twentieth and twenty-first-century texts and films from Hispanic America and Spain. Emphasis is on developing strategies for analyzing the genres of the novel, the short story, the poem, the fictional film, and the theatrical script. The novels read this semester are Magali García Ramis's Felices días, Tío Sergio (1986, Puerto Rico) and Javier Cercas's Soldados de Salamina (2001, Spain). We will study Lorca's play "La casa de Bernarda Alba" (1936, Spain), films from Spain, México, and Cuba, poems by Darío (Nicaragua), Machado (Spain), Lorca (Spain), Hernández (Spain), Vallejo (Perú), Cernuda (Spain), and Luis Palés Matos (Puerto Rico), and short stories from México (by an exiled Spanish writer), Chile, Argentina, and Cuba. Thematic emphasis is on the Spanish Civil War, changing attitudes toward gender, the Spanish-speaking Caribbean, and the history of race in the Americas.
This course has several purposes. The major concern will be the examination of Spanish culture including Spain's history, architecture, art, literature and film, to determine if there is a uniquely Spanish manner of seeing and understanding the world - one which emerges as clearly distinct from our own and that of other Western European nations.
This course explores artistic achievement in a culture that over the past century has engaged in constant and intense imaginative self-renewal. The class studies film, narrative (e.g., Márquez's One Hundred Years of Solitude), and poetry. Conducted in Spanish.
In this class we will come to understand the vast changes in Spanish life that have taken place since Franco's death in 1975. We will focus on the new freedom from censorship, the re-emergence of movements for regional autonomy, the new cinema, reforms in education and changes in daily life: sex roles, work, and family that have occurred in the last decade. In so doing, we will examine myths that are often considered commonplaces when describing Spain and its people.
This course provides an introduction to the language and culture of the Portuguese-speaking world, with special attention to Brazilian Portuguese. This course focuses are on basic oral expression, listening comprehension, and elementary reading and writing. Students develop their vocabulary and understanding of grammatical concepts through active communication. This is a coordinated language lab program and is designed for students with no knowledge of Portuguese. Class is conducted entirely in Portuguese.
This course is a continuation of 21F.801. It focuses on expanding communication skills and further development of linguistic competency using a variety of authentic sources, such as the Internet, audio, video, and printed materials, to help develop cultural awareness and linguistic proficiency. This course is conducted entirely in Portuguese.
This course is a collaborative offering of Sana, Partners in Health, and the Institute for Healthcare Improvement (IHI). The goal of this course is the development of innovations in information systems for developing countries that will (1) translate into improvement in health outcomes, (2) strengthen the existing organizational infrastructure, and (3) create a collaborative ecosystem to maximize the value of these innovations. The course will be taught by guest speakers who are internationally recognized experts in the field and who, with their operational experiences, will outline the challenges they faced and detail how these were addressed.
This course covers the growth, development and structure of normal bone and joints, the biomechanics of bone connective tissues, and their response to stress, calcium and phosphate homeostasis. Additional topics include regulation by parathyroid hormone and vitamin D, the pathogenesis of metabolic bone diseases and diseases of connective tissues, joints and muscle with consideration of possible mechanisms and underlying metabolic derangements.
Lecturers
Dr. Paul Joseph Anderson
Dr. Robert Horatio Brown, Jr.
Dr. Marie Demay
Dr. Stephen Martin Krane
Dr. Young-Jo Kim
Dr. Henry Jay Mankin
Dr. Bjorn Reino Olsen
Dr. John Thomas Potts
Dr. Alan Lewis Schiller
Dr. Brian Dale Snyder
This course provides a comprehensive overview of human pathology with emphasis on mechanisms of disease and diagnostic medicine. Topics include:
- Cellular Mechanisms of Disease
- Molecular Pathology
- Pathology of Major Organ Systems
- Review of Diagnostic Tools from Traditional Surgical Pathology to Diagnostic Spectroscopy
- Functional and Molecular Imaging
- Molecular Diagnostics
In addition to lectures, one of the two weekly sessions includes a 2-3 hour laboratory component. Periodically, time will also be devoted to minicases.
Lecturers
Prof. Jon Aster
Prof. Frederick Bieber
Prof. Carlo Brugnara
Prof. Robert B. Colvin
Prof. Christopher Crum
Prof. Douglas Dockery
Prof. Mel Feany
Prof. Michael Feld
Prof. Jonathan Fletcher
Prof. Michael Gimbrone
Prof. Todd Golub
This course is designed to give the student a clear understanding of the pathophysiology of the menstrual cycle, fertilization, implantation, ovum growth development, differentiation and associated abnormalities. Disorders of fetal development including the principles of teratology and the mechanism of normal and abnormal parturition will be covered as well as the pathophysiology of the breast and disorders of lactation. Fetal asphyxia and its consequences will be reviewed with emphasis on the technology currently available for its detection. In addition the conclusion of the reproductive cycle, menopause, and the use of hormonal replacement will be covered.
The most recent knowledge of the anatomy, physiology, biochemistry, biophysics, and bioengineering of the gastrointestinal tract and the associated pancreatic, liver and biliary tract systems is presented and discussed. Gross and microscopic pathology and the clinical aspects of important gastroenterological diseases are then presented, with emphasis on integrating the molecular, cellular and pathophysiological aspects of the disease processes to their related symptoms and signs.
The course will span modern neuroscience from molecular neurobiology to perception and cognition, including the following major topics: anatomy and development of the brain; cell biology of neurons and glia; ion channels and electrical signaling; synaptic transmission, integration, and chemical systems of the brain; sensory systems, from transduction to perception; motor systems; and higher brain functions dealing with memory, language, and affective disorders.
The object of the course is to teach students an approach to the study of pharmacologic agents. It is not intended to be a review of the pharmacopoeia. The focus is on the basic principles of biophysics, biochemistry and physiology, as related to the mechanisms of drug action, biodistribution and metabolism. The course consists of lectures and student-led case discussions. Topics covered include: mechanisms of drug action, dose-response relations, pharmacokinetics, drug delivery systems, drug metabolism, toxicity of pharmacological agents, drug interaction and substance abuse. Selected agents and classes of agents are examined in detail.
Lecturers
Prof. Keith Baker
Dr. Mark Dershwitz
Harold Demonaco
Dr. Daniel Kohane
Dr. Donald Kufe
Prof. Robert Langer
Dr. Robert Lees
Dr. Robert Rubin
Dr. Jeremy Ruskin
Prof. Thomas Spitzer
Prof. Carol Walsh
Dr. Michael Weinblatt
Dr. Warren Zapol
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This course provides a foundation for understanding the relationship between molecular biology, developmental biology, genetics, genomics, bioinformatics, and medicine. It develops explicit connections between basic research, medical understanding, and the perspective of patients. Principles of human genetics are reviewed. We translate clinical understanding into analysis at the level of the gene, chromosome and molecule; we cover the concepts and techniques of molecular biology and genomics, and the strategies and methods of genetic analysis, including an introduction to bioinformatics. Material in the course extends beyond basic principles to current research activity in human genetics.
This course covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation, including molecular structure and assembly of MHC molecules, the biology of cytokines, leukocyte-endothelial interactions, and the pathogenesis of immunologically mediated diseases. The course is structured as a series of lectures and tutorials in which clinical cases are discussed with faculty tutors.
Lecturers
Frederick W. Alt
Marcus Altfeld
Paul Anderson
Jon C. Aster
Hugh Auchincloss
Steven P. Balk
Samuel M. Behar
Richard S. Blumberg
Francisco Bonilla
Bobby Cherayil
Benjamin Davis
David Hafler
Nir Harcohen
Bruce Horwitz
David M. Lee
Andrew Lichtman
Diane Mathis
Richard Mitchell
Hidde Ploegh
Emmett Schmidt
Arlene Sharpe
Megan Sykes
Shannon Turley
Dale T. Umetsu
Ulrich von Andrian
Bruce Walker
Kai Wucherpfennig
Ramnik Xavier
Sarah Henrickson