Online courses directory (2511)

The goal of this class is to prove that category theory is a powerful language for understanding and formalizing common scientific models. The power of the language will be tested by its ability to penetrate into taken-for-granted ideas, either by exposing existing weaknesses or flaws in our understanding, or by highlighting hidden commonalities across scientific fields.

The causes and prevention of interstate war are the central topics of this course. The course goal is to discover and assess the means to prevent or control war. Hence we focus on manipulable or controllable war-causes. The topics covered include the dilemmas, misperceptions, crimes and blunders that caused wars of the past; the origins of these and other war-causes; the possible causes of wars of the future; and possible means to prevent such wars, including short-term policy steps and more utopian schemes.

The historical cases covered include the Peloponnesian and Seven Years wars, World War I, World War II, Korea, the Arab-Israel conflict, and the U.S.-Iraq and U.S. al-Queda wars.

This is an undergraduate course, but it is open to graduate students.

This course explores the causes of modern war with a focus on preventable causes. Course readings cover theoretical, historical, and methodological topics. Major theories of war are explored and assessed in the first few weeks of the class, asking at each stage "are these good theories?" and "how could they be tested?" Basic social scientific inference -- what are theories? What are good theories? How should theories be framed and tested? -- and case study methodology are also discussed. The second half of the course explores the history of the outbreak of some major wars. We use these cases as raw material for case studies, asking "if these episodes were the subject of case studies, how should those studies be performed, and what could be learned from them?"

This course explores the major areas of cellular and molecular neurobiology, including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell-type determination, axon guidance, neuronal cell biology, neurotrophin signaling and cell survival, synapse formation and neural plasticity. Material includes lectures and exams, and involves presentation and discussion of primary literature. It focuses on major concepts and recent advances in experimental neuroscience.

This course deals with the biology of cells of higher organisms: The structure, function, and biosynthesis of cellular membranes and organelles; cell growth and oncogenic transformation; transport, receptors, and cell signaling; the cytoskeleton, the extracellular matrix, and cell movements; chromatin structure and RNA synthesis.

The goal of this course is to teach both the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Lectures and class discussions will cover the background and fundamental findings in a particular area of nuclear cell biology. The assigned readings will provide concrete examples of the experimental approaches and logic used to establish these findings. Some examples of topics include genome and systems biology, transcription, and gene expression.

Mechanical forces play a decisive role during development of tissues and organs, during remodeling following injury as well as in normal function. A stress field influences cell function primarily through deformation of the extracellular matrix to which cells are attached. Deformed cells express different biosynthetic activity relative to undeformed cells. The unit cell process paradigm combined with topics in connective tissue mechanics form the basis for discussions of several topics from cell biology, physiology, and medicine.

Life as an emergent property of networks of chemical reactions involving proteins and nucleic acids. Mathematical theories of metabolism, gene regulation, signal transduction, chemotaxis, excitability, motility, mitosis, development, and immunity. Applications to directed molecular evolution, DNA computing, and metabolic and genetic engineering.

This course covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation, including molecular structure and assembly of MHC molecules, the biology of cytokines, leukocyte-endothelial interactions, and the pathogenesis of immunologically mediated diseases. The course is structured as a series of lectures and tutorials in which clinical cases are discussed with faculty tutors.

Lecturers