Online courses directory (2511)

This course provides an in-depth technical and policy analysis of various options for the nuclear fuel cycle. Topics include uranium supply, enrichment fuel fabrication, in-core physics and fuel management of uranium, thorium and other fuel types, reprocessing and waste disposal. Also covered are the principles of fuel cycle economics and the applied reactor physics of both contemporary and proposed thermal and fast reactors. Nonproliferation aspects, disposal of excess weapons plutonium, and transmutation of actinides and selected fission products in spent fuel are examined. Several state-of-the-art computer programs are provided for student use in problem sets and term papers.

This course provides an introduction to linear systems, transfer functions, and Laplace transforms. It covers stability and feedback, and provides basic design tools for specifications of transient response. It also briefly covers frequency-domain techniques.

 

This course provides an introduction to cellular and population-level systems biology with an emphasis on synthetic biology, modeling of genetic networks, cell-cell interactions, and evolutionary dynamics. Cellular systems include genetic switches and oscillators, network motifs, genetic network evolution, and cellular decision-making. Population-level systems include models of pattern formation, cell-cell communication, and evolutionary systems biology.

This course introduces the mathematical modeling techniques needed to address key questions in modern biology. An overview of modeling techniques in molecular biology and genetics, cell biology and developmental biology is covered. Key experiments that validate mathematical models are also discussed, as well as molecular, cellular, and developmental systems biology, bacterial chemotaxis, genetic oscillators, control theory and genetic networks, and gradient sensing systems. Additional specific topics include: constructing and modeling of genetic networks, lambda phage as a genetic switch, synthetic genetic switches, circadian rhythms, reaction diffusion equations, local activation and global inhibition models, center finding networks, general pattern formation models, modeling cell-cell communication, quorum sensing, and finally, models for Drosophila development.

This course introduces the mathematical modeling techniques needed to address key questions in modern biology. An overview of modeling techniques in molecular biology and genetics, cell biology and developmental biology is covered. Key experiments that validate mathematical models are also discussed, as well as molecular, cellular, and developmental systems biology, bacterial chemotaxis, genetic oscillators, control theory and genetic networks, and gradient sensing systems. Additional specific topics include: constructing and modeling of genetic networks, lambda phage as a genetic switch, synthetic genetic switches, circadian rhythms, reaction diffusion equations, local activation and global inhibition models, center finding networks, general pattern formation models, modeling cell-cell communication, quorum sensing, and finally, models for Drosophila development.

Systems Engineering is an interdisciplinary approach and means to enable the realization of successful systems. It focuses on defining customer needs and required functionality early in the development cycle, documenting requirements, then proceeding with design synthesis and system validation while considering the complete problem including operations, performance, test, manufacturing, cost, and schedule. This subject emphasizes the links of systems engineering to fundamentals of decision theory, statistics, and optimization. It also introduces the most current, commercially successful techniques for systems engineering.